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Exodus 2 Mouse
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Exodus-2 Mouse Recombinant
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CHM-371
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Catalogue number
CHM-371
Synonyms
Small inducible cytokine A21, CCL21, Beta chemokine exodus-2, 6Ckine, Secondary lymphoid-tissue chemokine, SLC, chemokine ligand 21, ECL, CKb9, TCA4, SCYA21, MGC34555.
Introduction
趋化因子配体 21 是属于 CC 趋化因子家族的小细胞因子。 这种趋化因子也称为 6Ckine、exodus-2 和次级淋巴组织趋化因子。 CCL21 主要在淋巴结中表达,与其他 CC 趋化因子相比,它对淋巴细胞具有趋化性。 CCL21 的基因位于人类第 9 号染色体上。CCL21 通过与称为 CCR7 的细胞表面趋化因子受体结合来引发其作用。
Description
Exodus-2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 110 amino acids and having a molecular mass of 12kDa.
The CCL21 is purified by proprietary chromatographic techniques.
The CCL21 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a concentrated solution in water containing 20mM Phosphate buffer and 0.15M NaCl pH-7.4.
Solubility
It is recommended to reconstitute the lyophilized Exodus2 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions
Stability
Lyophilized Exodus-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL21 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein . Please prevent freeze-thaw cycles.
Purity
Greater than 97.0% as determined by -PAGE & RP-HPLC.
Amino acid sequence
SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG.
Biological Activity
Determined by its ability to chemoattract total murine T cell population using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.
Usage
Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
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Exodus 2 Human
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Exodus-2 Mouse, Sf9