ProSpec-GRO g Human,GRO-伽玛人类重组CHM-310

  • GRO g Human

  • GRO-Gamma Human Recombinant
  • CHM-310

Catalogue number

CHM-310

Synonyms

Macrophage inflammatory protein 2-beta, MIP2-beta, CXCL3, Growth-regulated protein gamma, GRO-gamma, GRO-gamma, GRO3, GROg, MIP2B, SCYB3, MIP-2b, CINC-2b, MGSA gamma.

Introduction

趋化因子配体 3 是属于 CXC 趋化因子家族的小细胞因子,也称为 GRO3 癌基因、GRO 蛋白 γ 和巨噬细胞炎症蛋白-2-β。 CXCL3 控制单核细胞的迁移和粘附,并通过与称为 CXCR2 的细胞表面趋化因子受体相互作用介导其对靶细胞的影响。 CXCL3 基因位于其他 CXC 趋化因子簇中的 4 号染色体上。

Description

GRO-Gamma Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7902 Dalton.
The CXCL3 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The protein was lyophilized with no additives.

Solubility

It is recommended to reconstitute the lyophilized CXCL3 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized GRO-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL3 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Ser-Val-Val-Thr.

Biological Activity

The Biological activity is calculated by its ability to chemoattract CXCR2 transfected 293 cells using 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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