ProSpec,CCL3L1 Human,LD78-beta 人重组CHM-263

  • CCL3L1 Human

  • LD78-beta Human Recombinant
  • CHM-263

Catalogue number

CHM-263

Synonyms

C-C motif chemokine 3-like 1, G0/G1 switch regulatory protein 19-2, LD78-beta, PAT 464.2, Small-inducible cytokine A3-like 1, Tonsillar lymphocyte LD78 beta protein, CCL3L1, D17S1718, G0S19-2, SCYA3L1, LD78, 464.2, SCYA3L, LD78BETA, MGC12815.

Introduction

CCL3L1 is a small cytokine that belongs to the CC chemokines. The CCL3L1 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. CCL3L1 is involved in immunoregulatory and inflammatory processes. CCL3L1 binds to several chemokine receptors including CCBP2 and CCR5. CCR5 is a co-receptor for HIV, and binding of the CCL3L1 protein to CCR5 inhibits HIV entry.
CCL3L1 是一种属于 CC 趋化因子的小细胞因子。 CCL3L1 基因是聚集在 17 号染色体 q 臂上的几个细胞因子基因之一。CCL3L1 参与免疫调节和炎症过程。 CCL3L1 与几种趋化因子受体结合,包括 CCBP2 和 CCR5。 CCR5 是 HIV 的共受体,CCL3L1 蛋白与 CCR5 的结合可抑制 HIV 进入。

Description

CCL3L1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7.7kDa. The CCL3L1 is purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 CCL3L1 Human Recombinant 是一条单一的、非糖基化的多肽链,包含 70 个氨基酸,分子量为 7.7kDa。 CCL3L1 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized CCL3L1 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CCL3L1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL3L1 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA.

Biological Activity

The biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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