ProSpec,Lymphotactin Human His,CHM-357

  • Lymphotactin Human, His

  • Lymphotactin Human Recombinant , His Tag
  • CHM-357

Catalogue number

CHM-357

Synonyms

XCL1, Cytokine SCM-1, ATAC, Lymphotaxin, SCM-1-alpha, Small inducible cytokine C1, XC chemokine ligand 1, LTN, LPTN, SCM1, SCM-1, SCYC1, SCM-1a.

Introduction

XCL1 is a small cytokine belonging to the XC chemokine family that is also known as lymphotactin. It is located in high levels in spleen, thymus, intestine and peripheral blood leukocytes, and at lower levels in lung, prostate gland and ovary. Cellular sources for XCL1 include activated thymic and peripheral blood CD8+ T cells. This chemokine attracts T cells. In humans, XCL1 is closely related to another chemokine called XCL2, whose gene is found at the same locus on chromosome 1. XCL1 induces it chemotactic function by binding to a chemokine receptor called XCR1.
XCL1 是属于 XC 趋化因子家族的一种小细胞因子,也称为淋巴趋化素。 它在脾脏、胸腺、肠和外周血白细胞中含量较高,在肺、前列腺和卵巢中含量较低。 XCL1 的细胞来源包括活化的胸腺和外周血 CD8+ T 细胞。 这种趋化因子会吸引 T 细胞。 在人类中,XCL1 与另一种称为 XCL2 的趋化因子密切相关,后者的基因位于 1 号染色体的同一位点。XCL1 通过与称为 XCR1 的趋化因子受体结合来诱导其趋化功能。

Description

XCL1 Human Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 114 amino acids and having a molecular mass of 12.5 kDa. The XCL1 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 XCL1 Human Recombinant 是一条单一的、非糖基化的多肽链,包含 114 个氨基酸,分子量为 12.5 kDa。 XCL1 在 N 端与 20 个氨基酸的 His 标签融合,并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

Recombinant XCL1 contains 20mM Tris buffer pH-8, 200mM NaCl, 2mM DTT and 30% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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