ProSpec,NAP 2 Human CHM-274,中性粒细胞活化蛋白 2 人重组体CHM-274

  • NAP 2 Human

  • Neutrophil Activating Protein-2 Human Recombinant
  • CHM-274
  • Catalogue number

CHM-274

Synonyms

Platelet basic protein, PBP, Small inducible cytokine B7, CXCL7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, pro-platelet basic protein ligand 7), TC1, TC2, TGB, TGB1, B-TG1, CTAP3, NAP-2, SCYB7, THBGB, LA-PF4, THBGB1, Beta-TG, CTAPIII, CTAP-III.

Introduction

Chemokine ligand is a small cytokine belonging to the CXC chemokine family. It is a protein that is released in large amounts from platelets following their activation. It stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator.
趋化因子配体是属于 CXC 趋化因子家族的小细胞因子。 它是一种在血小板活化后从血小板中大量释放的蛋白质。 它刺激各种过程,包括有丝分裂、细胞外基质的合成、葡萄糖代谢和纤溶酶原激活剂的合成。

Description

Neutrophil Activating Protein-2 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 70 amino acids and having a molecular mass of 7609 Dalton.
The NAP-2 is purified by proprietary chromatographic techniques.
Neutrophil Activating Protein-2 Human Recombinant 在大肠杆菌中产生,是一种非糖基化的多肽链,含有 70 个氨基酸,分子量为 7609 道尔顿。
NAP-2 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The CXCL7 protein was lyophilized from a concentrated sterile solution containing no additives.

Solubility

It is recommended to reconstitute the lyophilized Neutrophil Activating Protein-2in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized NAP-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL7should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Glu-Leu-Arg-Cys.

Biological Activity

The specific activity as determined by the ability of NAP2 to chemoattract human neurotrophils using a concentration of 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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