ProSpec,PF 4 Mouse CHM-245,血小板因子 4 小鼠重组CHM-245

  • PF 4 Mouse

  • Platelet Factor-4 Mouse Recombinant
  • CHM-245

Catalogue number

CHM-245

Synonyms

CXCL4, PF-4, PF4, Iroplact, Oncostatin-A, SCYB4, MGC138298.

Introduction

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets. Its major physiologic role appears to be neutralization of molecules on the endothelial surface of blood vessels, thereby inhibiting local activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. Oncostatin-A is a member of the CXC chemocinfamily.

血小板因子 4 是一种由 70 个氨基酸组成的蛋白质,由活化血小板的 α 颗粒释放。 它的主要生理作用似乎是中和血管内皮表面的分子,从而抑制局部活性并促进凝血。 作为中性粒细胞和成纤维细胞的强化学引诱剂,PF4 可能在炎症和伤口修复中发挥作用。 Oncostatin-A 是 CXC 趋化素家族的成员。

Description

CXCL4 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 76 amino acids and having a molecular mass of 8.2kDa.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered white lyophilized powder.

Formulation

The Mouse CXCL4 protein was lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4 and 1.5M NaCl.

Solubility

It is recommended to reconstitute the lyophilized CXCL4 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CXCL4 Mouse Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Mouse CXCL4 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.
冻干的 CXCL4 小鼠重组体虽然在室温下稳定 3 周,但应在 -18°C 以下干燥储存。 重组后,小鼠 CXCL4 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。
对于长期储存,建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES.

Biological Activity

Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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