3,3′-亚甲基二吲哚
3,3′-Diindolylmethane(DIM)是indole-3-carbinol的主要消化产物，而indole-3-carbinol是十字花科蔬菜种一种潜在的抗癌物质。
理化数据
| 分子量 |
246.31 |
|
化学式 |
C17H14N2 |
|
CAS号 |
1968-05-4 |
|
稳定性 |
3 years 2-8°C powder |
|
2 years -80°C in solvent |
溶解性：
| DMSO |
49 mg/mL (198.93 mM) |
|
Ethanol |
18 mg/mL (73.07 mM) |
|
Water |
Insoluble |
生物活性
Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.
运输条件：常温运输
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