ProSpec-Activin B Human

 

  • Activin B Human

  • Activin-B Human Recombinant
  • CYT-058

Catalogue number

CYT-058

Synonyms

Inhibin beta B , Inhibin, beta-2, Activin beta-B chain, MGC157939.

Introduction

Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits.
Inhibins are thought to inhibit the production of follicle-stimulating hormone by the pituitary gland. In addition, Inhibins are also thought to play a role in the control of gametogenesis, and embryonic and fetal development.
抑制素是由雌性卵巢颗粒细胞和雄性支持细胞以及多种其他组织产生的二聚肽激素。 抑制素有两种同工型,A 和 B,具有相同的 α 亚基但不同的 β 亚基。 抑制素A是α和βA亚基的二聚体,抑制素B是α和βB亚基的二聚体。
抑制素被认为可以抑制垂体产生促卵泡激素。 此外,抑制素还被认为在控制配子发生、胚胎和胎儿发育中发挥作用。

Description

Activin B human Recombinant produced in Nicotiana benthamiana plant is a beta-B single chain containing 123 amino acids . Activin B is fused to a 10-His-tag at the N-terminal having the total molecular mass of 14kDa and purified by standard chromatographic techniques.
本氏烟草植物中产生的 Activin B human Recombinant 是一种含有 123 个氨基酸的 β-B 单链。 激活素 B 在 N 端与总分子量为 14kDa 的 10-His 标签融合,并通过标准色谱技术进行纯化。

Source

Nicotiana benthamiana plant

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from 1mg/ml solution in 0.05M Tris-HCl buffer pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized Activin B in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Activin B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Activin B should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.
冻干的 Activin B 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 复溶后,Activin B 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。 对于长期储存,建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by Analysis by -PAGE.

Amino acid sequence

HHHHHHHHHH GLECDGRTNL CCRQQFFIDF RLIGWNDWII APTGYYGNYC EGSCPAYLAG VPGSASSFHT AVVNQYRMRG LNPGTVNSCC IPTKLSTMSM LYFDDEYNIV KRDVPNMIVE ECG

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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