ProSpec-APOA1/CYT-037

Apolipoprotein A-I, Apo-AI, ApoA-I, APOA1, MGC117399.

APOA1 is a human protein with a specific role in lipid metabolism being the main protein component of HDL in the plasma. APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Furthermore, APOA1 is a cofactor for LCAT, which is responsible for the formation of most plasma cholesteryl esters. In addition, APOA1 activates spermatozoa motility as part of the SPAP complex. The APOA1 gene is strongly linked with two other apolipoprotein genes on chromosome 11. Defects in the APOA1 gene are linked to HDL deficiency including Tangier disease, and with systemic non-neuropathic amyloidosis. High levels of APOA1 are linked to the manifestation of asthma and atopy.

APOA1 是一种人类蛋白质，在脂质代谢中具有特定作用，是血浆中 HDL 的主要蛋白质成分。 APOA1 促进胆固醇从组织流出到肝脏进行排泄。 此外，APOA1 是 LCAT 的辅助因子，它负责大多数血浆胆固醇酯的形成。 此外，APOA1 作为 SPAP 复合物的一部分激活精子运动。 APOA1 基因与 11 号染色体上的其他两个载脂蛋白基因密切相关。APOA1 基因的缺陷与 HDL 缺乏症（包括丹吉尔病）和系统性非神经病性淀粉样变性有关。 高水平的 APOA1 与哮喘和特应性的表现有关。

APOA1 Human isolated from Human HDL is a single, glycosylated, polypeptide chain having a molecular mass of 28.3kDa. APOA1 is purified using delipidation and gel permeation chromatographic technique.

从人 HDL 中分离的 APOA1 Human 是一条单一的糖基化多肽链，分子量为 28.3kDa。 APOA1 使用脱脂和凝胶渗透色谱技术进行纯化。

Human HDL.

Sterile filtered colorless solution.

The APOA1 1mg/ml solution contains 10mM Ammonium Bicarbonate at pH7.4.

APOA1 although stable at 4°C for 1 week, should be stored below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze thaw cycles.

APOA1 虽然在 4°C 下稳定 1 周，但应储存在 -18°C 以下。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 95.0% as determined by -PAGE.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 它们不得用作药物、农业或农药产品、食品添加剂或家用化学品。